Midatech Pharma PLC (AIM:MTPH) Proposed New Chairman – MTX110 Study to be Presented

Midatech Pharma (MTPH), an R&D biotechnology company, said that Rolf Stahel, Chairman and non-executive director, intends to retire after the company’s AGM on 20 June 2022.

It is expected that Dr. Stephen Parker will be appointed as non-executive Chairman of the Board.

MTPH also revealed that investigators from Columbia University Irving Medical Center and New York-Presbyterian will present interim results from their ongoing Phase 1 study on Midatech’s MTX110 in Diffuse Intrinsic Pontine Glioma at The International Symposium on Pediatric Neuro-Oncology next week in Germany.

The presentation will take place on 13 June 2022 in the neurosurgery section of the conference, at 10.30 am CEST. The investigators will show first data on seven out of the ten planned patients on the safety of MTX110 (a water-soluble formulation of panobinostat) in patients with DIPG. This study uses an implantable pump and catheter system that allows for continuous intratumoral administration of the study drug without the need for repeated surgery. The study continues its recruitment.

The agenda of the meeting may be found here:

Scientific Program

Commenting, Dmitry Zamoryakhin, CSO of Midatech, said: “The presentation by the investigators from Columbia University Irving Medical Center and New York-Presbyterian will show first data on the safety of MTX110 use in patients with DIPG. This study uses an implantable pump and catheter system that allows for continuous intratumoral administration of the study drug without the need for repeated surgery. The same device is going to be used in another study of MTX110 in adult patients with recurrent glioblastoma, which we aim to begin in the second half of 2022.”


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